Follicular, Ovulatory, and Luteal Phases with and without PCOS: A model with clay

Two models are shown: one will show the normal development of tertiary follicles and dominant follicles, and the other will show the disrupted development in a woman with PCOS related to hormone imbalances.
This shows the follicular phase. As you can see, gonadotropin-releasing hormone (GnRH) stimulates follicle-stimulating hormone (FSH) and luteinizing hormone (LH) production. In the case of PCOS, too much LH is produced, resulting in several more follicles.
Continuing out the follicular phase, a dominant follicle produces estrogen, leading to a decrease in GnRH, LH, and FSH. In the ovary of a woman with PCOS, a dominant follicle does not emerge, and the regular estrogen production may not occur.
This shows the beginning of the ovulatory phase. The dominant follicle survives in the follicular phase, secretes estrogen, and triggers a positive feedback loop in that causes LH and FSH production to rise again. For a woman with PCOS, this positive feedback loop is never triggered.
During the luteal phase, the released oocyte travels towards the uterus while the granulosa and theca cells in the follicle form the corpus luteum, which produces progesterone. With PCOS, there is no corpus luteum and therefore no progesterone production.
One Comment
STEAM Projects

The Hormonal Effect on Maternal Protectiveness in Pregnancy

By nature, a mother post-partum is experiencing a hormone flux like she never has before. With certain senses feeling enhanced, and the baby forcing new responsibilities, the mother can often begin to feel an overwhelming need to nurture and protect their young. This feeling, or in some cases, maternal aggression, …

Uncategorized

Tia Campanelli 2023 STEAM Project- How The Nexplanon Birth Control Implant Hormonally Regulates Ovulation and Menses

STEAM Project Essay: Tia Campanelli  15 April, 2023 STEAM Project How The Nexplanon Birth Control Implant Hormonally Regulates Ovulation and Menses Out of the 72.2 million women in the United States 46.9 million of them are on some sort of contraceptive birth control. The conversation of beginning a course of …

STEAM Projects

STEMI

The learning objective that I am addressing in this paper is:  “Explain how the heart translates an electrical signal to a contraction” I will be looking at how you can use a 12 lead Electrocardiogram (ECG) to detect a ST- segment elevation myocardial infarction (STEMI) and predict where the ischemia …