My project demonstrates how prion disease is contracted and affects the body, using a humourous cartoon. It shows the cascading effects of protein misfolding as it spreads through the body and causes symptoms through changes in the nervous system. It simplifies prion disease to narrate the disease’s onset and development in a cartoon art style. It takes the perspective of prion proteins as an “organization” responsible for activating a zombie-like state through secret operations affecting the body and accomplishing nervous system breakdown as a mission. The comic’s conclusion also demonstrates the popular misunderstandings of the disease in historical and imaginative contexts, showing victims of the disease as “mad” zombies, playing with popular brain-eating zombie portrayals, and connecting them to the actual transmission of CJD or Kuru.