The Hygiene Hypothesis: A Modern Application 40 Years Later

Nearly 40 years ago, David P Strachan published a study in the British Medical Journal which discussed data correlating the onset of childhood allergies and household size and cleanliness in British children (Strachan 1998). This so called “hygiene hypothesis” found an interesting trend: on average, children born to large households …

Prions: Huntington’s Disease (by Shannon McCallum and Mesa Moran)

In this project, we demonstrated how hydrogen bonds determine the functionality of a protein. We chose to highlight Huntington’s Disease, which is caused by a trinucleotide repeat of the amino acid glutamine, a polar molecule. The extension of the Huntingtin gene rearranges hydrogen bonds in the Huntingtin protein, causing it …