Posted by Mari Bell on April 20, 2023 April 20, 2023 STEAM Projects Von Willebrand disease is a blood disorder where blood cannot clot properly, causing symptoms like heavier and longer-lasting bleeding after an injury.On the left side of my art piece, I wanted to creatively depict how proteins in the blood, more specifically von Willebrand factor, help in the process of hemostasis. In the sky, I show red blood cells in red discs, unactivated and activated platelets in white, and coiled and uncoiled von Willebrand factor in light purple. Higher in the piece, coiled von Willebrand factor doesn’t interact with surrounding elements until it attaches to the injury site. Once it uncoils at the site, platelets that were once normal white dots, will attach to von Willebrand factor and activate, turning into star shapes. More and more platelets will attach and activate until a plug is formed to stop red blood cells and blood from leaking through. Because activated platelets looked so much like stars to me, I thought it would be fun to depict the process of hemostasis in the sky, depicting platelets as stars and von Willebrand factor as the lines that help form constellations.On the right side, I wanted to creatively show how the absence of von Willebrand factor, results in hemostasis failing to happen. I also wanted to show VWD uniquely by depicting it as rain falling on the person impacted by the symptoms of long and heavy bleeding.