Essential (Acquired) Cold Urticaria and the Immune System

“Frosty Reactions: A Limerick Tale of Cold Urticaria”When cold strikes the skin with a breeze,Mast cells react with such ease.Histamine they release,Causing hives and unease,In a rash that’s quick to appease.Histamine’s role is quite clear,It makes blood vessels shift gear.With swelling and itch,It can cause quite a hitch,Turning skin red …