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  1. Ulcerative colitis is a disease characterized by the inflammation of the colon and a chronic state of immobility in its victims. It causes the majority of the large intestine to lose its function in absorbing excess water and nutrients from fecal matter. There is no cure due to its infancy in research, physicians still do not know what the main causes of ulcerative colitis are and, in turn, no method to cure this ailment. The reason there is so little known is due to this illness’s similarity in genes with other autoimmune disorders such as psoriasis, making it rather ambiguous to track genetically. Furthermore, inflammation is a very general response towards immunity, further muddling the road towards our knowledge of the illness. Some hypotheses surrounding its causes are linked to overactivity in the body’s immune system, similar to other digestive disorders such as Crohn’s disease.

    This project’s piece is a depiction of a comparison and contrast between a healthy colon, and one affected by ulcerative colitis. The difference is seen clearly, with the unhealthy colon having an increase in ridges, and inflamed, damaged tissue. Other physical symptoms of a colon affected by ulcerative colitis include ulcers, formed by white blood cells meant to target pathogens in the large intestine. These ulcers can be formed due to the cessation of mucosal flow that was once protecting the colon. These ulcers and inflammation often cause bleeding in the colon as well as diarrhea and dehydration due to the lack of water being absorbed before defecation.

    Razan Yousif

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