1. This is really just a drawing of what a normal lung and a lung that is diseased with cystic fibrosis looks like. Below is a Haematoxylin and eosin stained examinations of the lung tissue. On the left is what a normal lung tissue is supposed to look like, while on the right is one with cystic fibrosis.

    Jessup Hanson
  2. Jessup did his project on how cystic fibrosis effects the lungs, specifically on how it effects on the alveolar spaces. Jessup explains in the essay portion how cystic fibrosis is genetic by passing down the cystic fibrosis transmembrane conductance regulator, if you have two of these genes you are susceptible to cystic fibrosis. This gene does not determine whether you get cystic fibrosis by itself or not because this gene controls the CFTR protein which its function is to maintain the balance of salt and water in the body. Cystic fibrosis forms when there is one CFTR gene that mutates that will disrupt the salt and water balance in the body. However you can have a mutated gene as long as there is a normal gene in the system to balance it out and neutralize the genes. Transitioning from the gene pool part Jeseup talks about how cystic fibrosis is formed when chloride becomes trapped in the cells. Jessup does well in explaining how cystic fibrosis is formed starting from the molecular level within genes, cells, and proteins. Additionally as Jessup states in the essay the answer to knowing why these cells mutate in the first place is still unknown. Jessup also states in the essay that while there is no cure, there are treatments options as to lessening the symptoms and to maintain cystic fibrosis to not get worse. Jessup drew a picture of lungs and how they look healthy, vs how they look when cystic fibrosis infects and stains the lung tissue. Jessup also draws what the alveolar spaces should look like and that are healthy, vs what they look like after being infected, inflamed, and the immune cells attempting to fight this off. Jessup drew what both look like because while cystic fibrosis effects the whole lungs, it mostly effects the alveolar spaces located in the lungs

    Kailani Smith

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