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  1. Abstract: (after reading paper)
    Tissue engineering is a field that combines biology, chemistry, and engineering in order to repair and tissue damage and organ damage. Utilizing a mixture of stem cells, biomaterial, and bioactive molecules, tissue engineering pursues the goal of restoring critical function to tissues and organs. Recent developments in biomimetic natural biomaterials have improved the rate and efficiency for restoring damaged tissue.

    Alginate, extracted from brown seaweed, supports long term cell culturing along with usage in scaffolds and fibers. Cellulose is the most abundant biomaterial and is critical for clinical application due to its compatibility and degradability. Hyaluronic acid, which is critical for tissue repair, is created in engineered bacteria.

    Tissue engineering has seen success in orthopedics, cardiovascular medicine, and wound healing. With bioactive materials fostering osteogenesis, vascular repair, and more efficient wound healing. While challenges remain replicating natural ECM and matching the mechanical properties of tissues, future research aims to focus on developing smart biomaterial response to physiological environments.

    Korbin Bowker-Kuhnen

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